Conclusion de l’atelier
- Tenir compte des recommandations ci-dessus en tant que guidelines
- Mise en place d’un comité d’experts. Porte d’entrée : registre France Greffe de Moelle (FGM) ; participants: membres du groupe de travail SFGM-TC
- Objectif: aide à la décision du choix du greffon de sang placentaire (SP) si besoin est exprimé par un centre greffeur
- Evaluation du suivi des recommandations par les centres greffeurs
Questions résiduelles à explorer
- Quelle dose cellulaire chez l’obèse ? adaptation sur poids idéal.
- Quand recruter l’USP de secours « back-up » ?
- Intérêt du typage élargi (niveau allélique classe I, HLA-C et DQ) NIMA
- Greffe phéno identique 9/10 vs greffe de sang placentaire ?
- Impact de la dose cellulaire et du type de conditionnement ?
- Evaluer l’impact de la compatibilité HLA entre les 2 USP
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